Article
Temperature differentially facilitates spontaneous but not evoked glutamate release from cranial visceral primary afferents.
PloS one - 1 Jan 2015
Fawley Jessica A, Hofmann Mackenzie E, Largent-Milnes Tally M, Andresen Michael C
Abstract excerpt
Temperature is fundamentally important to all biological functions including synaptic glutamate release. Vagal afferents from the solitary tract (ST) synapse on second order neurons in the nucleus of the solitary tract, and glutamate release at this first central synapse controls autonomic reflex function. Expression of the temperature-sensitive Transient Receptor Potential Vanilloid Type 1 receptor separates ST...
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