Article
Cellular Sensing of Viral DNA and Viral Evasion Mechanisms
27 Jun 2014
Abstract excerpt
Mammalian cells detect foreign DNA introduced as free DNA or as a result of microbial infection, leading to the induction of innate immune responses that block microbial replication and the activation of mechanisms that epigenetically silence the genes encoded by the foreign DNA. A number of DNA sensors localized to a variety of sites within the cell have been identified, and this review focuses on the mechanisms...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
