Software for the analysis and visualization of deep mutational scanning data.

Abstract excerpt

BACKGROUND: Deep mutational scanning is a technique to estimate the impacts of mutations on a gene by using deep sequencing to count mutations in a library of variants before and after imposing a functional selection. The impacts of mutations must be inferred from changes in their counts after selection. RESULTS: I describe a software package, dms_tools, to infer the impacts of mutations from deep mutational...

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