Article
gyōza: a Snakemake workflow for modular analysis of deep-mutational scanning data.
Genetics - 7 Jan 2026
Durand Romain, Pageau Alicia, Landry Christian R
Abstract excerpt
Deep-mutational scanning (DMS) is a powerful technique that allows screening large libraries of mutants at high throughput. It has been used in many applications, including to estimate the fitness impact of all single mutants of entire proteins, to catalog drug resistance mutations, and even to predict protein structures. Here, we present gyōza, a Snakemake-based workflow to analyze DMS data. gyōza requires...
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