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Article

Inflammatory environment and oxidized LDL convert circulating human proangiogenic cells into functional antigen-presenting cells.

Journal of leukocyte biology - 1 Sept 2015

Vinci Maria Cristina, Piacentini Luca, Chiesa Mattia, Saporiti Federica, Colombo Gualtiero I, Pesce Maurizio

Abstract excerpt

The function of human circulating PACs has been described extensively. However, little focus has been placed on understanding how these cells differ in their functions in the presence of microenvironments mimicking vascular inflammation. We hypothesized that exposure to proinflammatory cytokines or the oxLDL, an autoantigen abundant in advanced atherosclerotic plaques, converts PACs into...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25990243
DOI: 10.1189/jlb.3A0814-412RR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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