Article
Blood and lymphatic endothelial cell-specific differentiation programs are stringently controlled by the tissue environment
9 Feb 2007
Abstract excerpt
The discovery of marker proteins of human blood (BECs) and lymphatic endothelial cells (LECs) has allowed researchers to isolate these cells. So far, efforts to unravel their transcriptional and functional programs made use of cultured cells only. Hence, it is unknown to which extent previously identified LEC- and BEC-specific programs are representative of the in vivo situation. Here, we define the human BEC-...
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