Article

Immunomodulatory endothelial cells contribute to T cell recruitment and activation through antigen presentation on MHC class II

2025-07-22

Abstract excerpt

<h4>Aims</h4> A subset of endothelial cells referred to as immunomodulatory endothelial cells (IMEC) has been proposed to regulate T cell responses in atherosclerosis, but their phenotype and function remain poorly understood. Here, we characterized the inflammation-induced emergence of IMEC and their crosstalk with T cells. <h4>Methods and Results</h4> An in vitro model to study IMEC was established and charac...

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Literature Corpus work: 6f6d5d8b-9f8e-5b43-bdd3-e7e5e5a94180
DOI: 10.1101/2025.07.17.665432

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