Article
Mutation Analysis of IDH1/2 Genes in Unselected De novo Acute Myeloid Leukaemia Patients in India - Identification of A Novel IDH2 Mutation.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Raveendran Sureshkumar, Sarojam Santhi, Vijay Sangeetha, Geetha Aswathy Chandran, Sreedharan Jayadevan, Narayanan Geetha, Sreedharan Hariharan
Abstract excerpt
IDH1/2 mutations which result in alternation in DNA methylation pattern are one of the most common methylation associated mutations in Acute myeloid leukaemia. IDH1/2 mutations frequently associated with higher platelet level, normal cytogentics and NPM1 mutations. Here we analyzed IDH1/2 mutations in 200 newly diagnosed unselected Indian adult AML patients and investigated their correlation with clinical,...
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