Article
Characterization of CEBPA Mutations and Polymorphisms and their Prognostic Relevance in De Novo Acute Myeloid Leukemia Patients.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Sarojam Santhi, Raveendran Sureshkumar, Vijay Sangeetha, Sreedharan Jayadevan, Narayanan Geetha, Sreedharan Hariharan
Abstract excerpt
The CCAAT/enhancer-binding protein-alpha (CEBPA) is a transcriptional factor that plays a crucial role in the control of proliferation and differentiation of myeloid precursors. This gene was recognized as the target of genetic alterations and were associated with clinical complexity among AML. We here analyze the frequency and types of CEBPA mutations and polymorphisms in a de novo AML patients from South India...
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