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Article

Beneficial effect of the CXCL12-3'A variant for patients undergoing hematopoietic stem cell transplantation from unrelated donors.

Cytokine - 1 Dec 2015

Bogunia-Kubik Katarzyna, Mizia Sylwia, Polak Małgorzata, Gronkowska Anna, Nowak Jacek, Kyrcz-Krzemień Sławomira, Markiewicz Mirosław, Dzierżak-Mietła Monika, Koclęga Anna, Sędzimirska Mariola, Suchnicki Krzysztof, Duda Dorota, Lange Janusz, Mordak-Domagała Monika, Kościńska Katarzyna, Jędrzejczak Wiesław Wiktor, Kaczmarek Beata, Hellmann Andrzej, Kucharska Agnieszka, Kowalczyk Jerzy, Drabko Katarzyna, Warzocha Krzysztof, Hałaburda Kazimierz, Tomaszewska Agnieszka, Mika-Witkowska Renata, Witkowska Agnieszka, Goździk Jolanta, Mordel Anna, Wysoczańska Barbara, Jaskula Emilia, Lange Andrzej

Abstract excerpt

The present study aimed to assess the impact of the CXCL12 gene polymorphism (rs1801157) on clinical outcome of hematopoietic stem cell transplantation from unrelated donors. Toxic complications were less frequent among patients transplanted from donors carrying the CXCL12-3'-A allele (42/79 vs. 105/151, p=0.014 and 24/79 vs. 73/151, p=0.009, for grade II-IV and III-IV, respectively). Logistic regression analyses...

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Source

Identifiers

PMID: 25982843
DOI: 10.1016/j.cyto.2015.05.001

Genes

CXCL12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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