Article
Genetics factors associated with myelodysplastic syndromes.
Blood cells, molecules & diseases - 1 Jun 2015
Macedo Luciana Conci, Silvestre Ana Paula Avenia, Rodrigues Camila, de Alencar Josiane Bazzo, Zacarias Joana Maira Valentini, Ambrosio-Albuquerque Eliane Papa, Sell Ana Maria, Visentainer Jeane Eliete Laguila
Abstract excerpt
The myelodysplastic syndromes (MDS) are a clinically and cytogenetically heterogeneous group of clonal diseases. Clonal chromosomal abnormalities are observed in 30-50% of patients with MDS. The deletions are among the most common alterations, and often involve the long arms of chromosomes 5, 7, 8, 13, and 20 and the short arms of chromosomes 12 and 17. The advent of new technologies for the detection of genetic...
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