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Article

The distinctive molecular, pathological and clinical characteristics of BRAF-mutant colorectal tumors.

Expert review of molecular diagnostics - 1 Jan 2015

Scartozzi Mario, Giampieri Riccardo, Aprile Giuseppe, Iacono Donatella, Santini Daniele, dell'Aquila Emanuela, Silvestris Nicola, Gnoni Antonio, Bonotto Marta, Puzzoni Marco, Demurtas Laura, Cascinu Stefano

Abstract excerpt

Several clinical series have demonstrated a notably low overall survival for colorectal cancer patients diagnosed with a BRAF-mutant tumor. A potentially interesting predictive role has also been suggested for BRAF-mutant colorectal cancer receiving anti-EGFR monoclonal antibodies. Although a global consensus exists in indicating BRAF as a prognostic factor with a possible predictive activity, the clinical use of...

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Identifiers

PMID: 25975986
DOI: 10.1586/14737159.2015.1047346

Genes

BRAF
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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