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Article

Anti-protozoal and anti-bacterial antibiotics that inhibit protein synthesis kill cancer subtypes enriched for stem cell-like properties.

Cell cycle (Georgetown, Tex.) - 1 Jan 2015

Cuyàs Elisabet, Martin-Castillo Begoña, Corominas-Faja Bruna, Massaguer Anna, Bosch-Barrera Joaquim, Menendez Javier A

Abstract excerpt

Key players in translational regulation such as ribosomes might represent powerful, but hitherto largely unexplored, targets to eliminate drug-refractory cancer stem cells (CSCs). A recent study by the Lisanti group has documented how puromycin, an old antibiotic derived from Streptomyces albonig...

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Identifiers

PMID: 25970790
DOI: 10.1080/15384101.2015.1044173
PMCID: PMC4825717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25970790-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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