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Article

Glycoform Separation and Characterization of Cetuximab Variants by Middle-up Off-Line Capillary Zone Electrophoresis-UV/Electrospray Ionization-MS.

Analytical chemistry - 16 Jun 2015

Biacchi Michael, Gahoual Rabah, Said Nassur, Beck Alain, Leize-Wagner Emmanuelle, François Yannis-Nicolas

Abstract excerpt

Monoclonal antibodies (mAbs) are highly complex glycoproteins that present a wide range of microheterogeneities that requires multiple analytical methods for full structure assessment and quality control. Capillary zone electrophoresis-mass spectrometry (CZE-MS) couplings, especially by electrosp...

Read the complete abstract on PubMed

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Share to Cetuximab
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Spectrometry, Mass, Electrospray Ionization

Share to Spectrophotometry, Ultraviolet

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Identifiers

PMID: 25970692
DOI: 10.1021/acs.analchem.5b00928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25970692-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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