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Article

Analytical characterization of IgG Fc subclass variants through high-resolution separation combined with multiple LC-MS identification.

Analytical and bioanalytical chemistry - 1 Sept 2015

He Xiaomei Annie, Washburn Nathaniel, Arevalo Enrique, Robblee John H

Abstract excerpt

With the rapid growth of recombinant monoclonal antibodies and intravenous immunoglobulin (IVIg) medicines, the understanding of human immunoglobulin G (IgG) subclasses becomes more necessary. It is essential to develop effective techniques and methodologies which have the capability for deep characterization. We have created an approach by applying LC and liquid chromatography-mass spectrometry (LC-MS) methods...

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Identifiers

PMID: 26231686
DOI: 10.1007/s00216-015-8863-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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