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Article

Toxic epidermal necrolysis induced by methazolamide in a Chinese-Korean man carrying HLA-B*59:01.

International journal of dermatology - 1 Nov 2015

Shu Chang, Shu Dan, Tie Duerna, Yu Mengqing, Zhang Rui, Wang Tong, Dong Qi, Sun Qiuning, Mao Xuming, Yan Yan

Abstract excerpt

BACKGROUND: Methazolamide is used to lower intraocular pressure in patients with glaucoma. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) associated with methazolamide treatment have been diagnosed in Korean, Japanese, and Japanese-American patients. According to recent research, the human leukocyte antigen (HLA) allele HLA-B*59:01 is strongly linked to SJS/TEN associated with methazolamide...

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Identifiers

PMID: 25970075
DOI: 10.1111/ijd.12651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Toxic epidermal necrolysis induced by methazolamide in a Chinese-Korean man carrying HLA-B*59:01.PMID 25970075Read ↗

HLA-B*59:01: a marker for Stevens-Johnson syndrome/toxic epidermal necrolysis caused by methazolamide in Han Chinese.Semantic proximity Read ↗

HLA-B*5901 is strongly associated with methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis.Semantic proximity Read ↗

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