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Article

Association between the HLA-B*15:02 allele and carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Han individuals of northeastern China.

Pharmacological reports : PR - 1 Jan 2013

He Xiao-Jing, Jian Ling-Yan, He Xiao-Lin, Wu Yan, Xu Yuan-Yuan, Sun Xiao-Jie, Miao Li-Yan, Zhao Li-Mei

Abstract excerpt

BACKGROUND: This study examined the significant association between carbamazepine (CBZ)-induced Stevens-Johnson Syndrome (SJS)/toxic epidermal necrolysis (TEN) and HLA-B*15:02 in epilepsy patients of Han ethnicity living in northeastern China. METHODS: CBZ-SJS/TEN patients and CBZ-tolerant control patients were genotyped for HLA-B*15:02 by PCR amplification using sequence-specific primers. Patients then were...

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Identifiers

PMID: 24399721
DOI: 10.1016/s1734-1140(13)71483-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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