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Analysis of Ocular Manifestation and Genetic Association of Allopurinol-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in South Korea.

Cornea - 1 Feb 2016

Lee Hyo Seok, Ueta Mayumi, Kim Mee Kum, Seo Kyoung Yul, Sotozono Chie, Kinoshita Shigeru, Yoon Kyung Chul

Abstract excerpt

PURPOSE: To describe the clinical characteristics and genetic background of allopurinol-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in South Korea. METHODS: This is a prospective, noncomparative case series. Visual acuity, detailed medical history, ocular findings, and systemic manifestations of 5 patients (10 eyes) with allopurinol-induced SJS/TEN were recorded. The acute ocular...

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PMID: 26655481
DOI: 10.1097/ICO.0000000000000708

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