Article

TRiC activates the unfolded protein response and protects starved stem cells by modulating energy and lipid metabolism during planarian regeneration

2019-08-12

Abstract excerpt

<h4>Summary</h4> Fasting protects stem cells and increases stem cell functionality through mechanisms which are not fully understood. Planarians are not only able to regenerate their bodies, but also to stand long periods of starvation by shrinking in size. This adaptation is possible because of a large population of adult stem cells which indefinitely self-renew even under starved conditions and thus confer plan...

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Literature Corpus work: 8deffecc-bcfd-57e9-8eed-f9c27805647c
DOI: 10.1101/732875

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