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Article

Receptor-Mediated Mechanism Controlling Tissue Levels of Bioactive Lipid Oxidation Products.

Circulation research - 31 Jul 2015

Kim Young-Woong, Yakubenko Valentin P, West Xiaoxia Z, Gugiu Gabriel B, Renganathan Kutralanathan, Biswas Sudipta, Gao Detao, Crabb John W, Salomon Robert G, Podrez Eugene A, Byzova Tatiana V

Abstract excerpt

RATIONALE: Oxidative stress is an important contributing factor in several human pathologies ranging from atherosclerosis to cancer progression; however, the mechanisms underlying tissue protection from oxidation products are poorly understood. Oxidation of membrane phospholipids, containing the polyunsaturated fatty acid docosahexaenoic acid, results in the accumulation of an end product,...

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Source

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Identifiers

PMID: 25966710
DOI: 10.1161/CIRCRESAHA.117.305925
PMCID: PMC4522201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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