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Article

Novel insights into the pleiotropic health effects of growth differentiation factor 11 gained from genome-wide association studies in population biobanks.

BMC genomics - 6 Sept 2024

Strosahl Jessica, Ye Kaixiong, Pazdro Robert

Abstract excerpt

BACKGROUND: Growth differentiation factor 11 (GDF11) is a member of the transforming growth factor-β (TGF-β) superfamily that has gained considerable attention over the last decade for its observed ability to reverse age-related deterioration of multiple tissues, including the heart. Yet as many researchers have struggled to confirm the cardioprotective and anti-aging effects of GDF11, the topic has grown...

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PMID: 39237910
DOI: 10.1186/s12864-024-10710-7
PMCID: PMC11378601

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