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Article

Clonally related uterine leiomyomas are common and display branched tumor evolution.

Human molecular genetics - 1 Aug 2015

Mehine Miika, Heinonen Hanna-Riikka, Sarvilinna Nanna, Pitkänen Esa, Mäkinen Netta, Katainen Riku, Tuupanen Sari, Bützow Ralf, Sjöberg Jari, Aaltonen Lauri A

Abstract excerpt

Uterine leiomyomas are extremely frequent benign smooth muscle tumors often presenting as multiple concurrent lesions and causing symptoms such as abnormal menstrual bleeding, abdominal pain and infertility. While most leiomyomas are believed to arise independently, a few studies have encountered...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25964426
DOI: 10.1093/hmg/ddv177

Genes

MED12
DEPDC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25964426-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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