Article
In vitro activity of daptomycin in combination with β-lactams, gentamicin, rifampin, and tigecycline against daptomycin-nonsusceptible enterococci.
Antimicrobial agents and chemotherapy - 1 Jul 2015
Hindler Janet A, Wong-Beringer Annie, Charlton Carmen L, Miller Shelley A, Kelesidis Theodoros, Carvalho Marissa, Sakoulas George, Nonejuie Poochit, Pogliano Joseph, Nizet Victor, Humphries Romney
Abstract excerpt
Enterococci that are nonsusceptible (NS; MIC > 4 μg/ml) to daptomycin are an emerging clinical concern. The synergistic combination of daptomycin plus beta-lactams has been shown to be effective against vancomycin-resistant Enterococcus (VRE) species in vitro. This study systematically evaluated by in vitro time-kill studies the effect of daptomycin in combination with ampicillin, cefazolin, ceftriaxone,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.