Article
Emergence of daptomycin non-susceptibility in colonizing vancomycin-resistant Enterococcus faecium isolates during daptomycin therapy.
International journal of medical microbiology : IJMM - 1 Dec 2015
Lellek Heinrich, Franke Gefion C, Ruckert Carolin, Wolters Manuel, Wolschke Christiane, Christner Martin, Büttner Henning, Alawi Malik, Kröger Nicolaus, Rohde Holger
Abstract excerpt
Infections due to vancomycin-resistant enterococci (VRE) are of significant importance in high-risk populations, and daptomycin is a bactericidal antibiotic to treat multidrug-resistant VRE in these patients. The emergence of daptomycin non-susceptibility invasive VRE during daptomycin therapy is a major clinical issue. Here the hypothesis was tested that systemic daptomycin therapy also induces the emergence of...
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