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Article

Genotype status of the dopamine-related catechol-O-methyltransferase (COMT) gene corresponds with desirability of "unhealthy" foods.

Appetite - 1 Sept 2015

Wallace Deanna L, Aarts Esther, d'Oleire Uquillas Federico, Dang Linh C, Greer Stephanie M, Jagust William J, D'Esposito Mark

Abstract excerpt

The role of dopamine is extensively documented in weight regulation and food intake in both animal models and humans. Yet the role of dopamine has not been well studied in individual differences for food desirability. Genotype status of the dopamine-related catechol-O-methyltransferase (COMT) gene has been shown to influence dopamine levels, with greater COMT enzymatic activity in val/val individuals...

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Source

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Identifiers

PMID: 25963102
DOI: 10.1016/j.appet.2015.05.004
PMCID: PMC4629853

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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