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Article

Prevalence and Spectrum of NKX2-5 Mutations Associated With Sporadic Adult-Onset Dilated Cardiomyopathy.

International heart journal - 3 Aug 2017

Xu Jia-Hong, Gu Jian-Yun, Guo Yu-Han, Zhang Hong, Qiu Xing-Biao, Li Ruo-Gu, Shi Hong-Yu, Liu Hua, Yang Xiao-Xiao, Xu Ying-Jia, Qu Xin-Kai, Yang Yi-Qing

Abstract excerpt

Dilated cardiomyopathy (DCM), the most common form of primary myocardial disease, is a leading cause of congestive heart failure and the most common indication for heart transplantation. Recently, NKX2-5 mutations have been involved in the pathogenesis of familial DCM. However, the prevalence and spectrum of NKX2-5 mutations associated with sporadic DCM remain to be evaluated. In this study, the coding regions...

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Source

Identifiers

PMID: 28690296
DOI: 10.1536/ihj.16-440

Genes

GATA4
TBX20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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