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Article

Sickle cell disease and H3Africa: enhancing genomic research on cardiovascular diseases in African patients.

Cardiovascular journal of Africa - 1 Jan 2000

Wonkam Ambroise, Makani Julie, Ofori-Aquah Solomon, Nnodu Obiageli E, Treadwell Marsha, Royal Charmaine, Ohene-Frempong Kwaku

Abstract excerpt

BACKGROUND: Sickle cell disease (SCD) has a high prevalence in sub-Saharan Africa. There are several cardiovascular phenotypes in SCD that contribute to its morbidity and mortality. DISCUSSION: SCD is characterised by marked clinical variability, with genetic factors playing key modulating roles. Studies in Tanzania and Cameroon have reported that singlenucleotide polymorphisms in BCL11A and HBS1L-MYB loci and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25962948
DOI: 10.5830/CVJA-2015-040
PMCID: PMC4547555

Genes

SCD
MYB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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