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Article

Uptake of CCR7 by KIR2DS4 + NK Cells Is Induced upon Recognition of Certain HLA-C Alleles

1 Jan 2015

Abstract excerpt

The KIR2DS4 receptor is the oldest KIR2DS expressed by human NK lymphocytes. The specificity of recognition of this receptor for various HLA class I alleles has been demonstrated; however it remains poorly understood whether these interactions may result in the activation of some specific functions in NK cells. Here, we examined the functional outcome of the KIR2DS4/HLA class I interaction by the use of an...

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PMID: 25961063
DOI: 10.1155/2015/754373

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