Article
COX-2 rs20417 Polymorphism Is Associated with Stroke and White Matter Disease.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Aug 2015
Oliveira-Filho Jamary, Ornellas Ana C P, Zhang Cathy R, Oliveira Luciana M B, Araújo-Santos Théo, Borges Valeria M, Ventura Laís M G B, Reis Francisco J F B, Aras Roque, Fernandes André M, Rosand Jonathan, Greenberg Steven M, Furie Karen L, Rost Natalia S
Abstract excerpt
BACKGROUND: To investigate the effect of COX-2 polymorphism and its product, prostaglandin E2 (PGE2), on stroke risk in an endemic area for Chagas disease. In a separate cohort, to investigate the effect of COX-2 polymorphisms on the total burden of cerebral white matter disease. METHODS: Cases were outpatients with ischemic stroke; controls were stroke-free subjects from 2 outpatient clinics (heart failure and...
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