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Article

Evaluation of a high throughput method for the detection of mutations associated with thrombosis and hereditary hemochromatosis in Brazilian blood donors.

PloS one - 1 Jan 2015

Dionisio Tavares Niewiadonski Vivian, Dos Santos Bianchi Juliana Vieira, de Almeida-Neto Cesar, Gaburo Nelson, Sabino Ester Cerdeira

Abstract excerpt

BACKGROUND: The aim of this study was to evaluate the OpenArray platform for genetic testing of blood donors and to assess the genotype frequencies of nucleotide-polymorphisms (SNPs) associated with venous thrombosis (G1691A and G20210A), hyperhomocysteinemia (C677T, A1298C), and hereditary hemochromatosis (C282Y, H63D and S65C) in blood donors from Sao Paulo, Brazil. METHODS: We examined 400 blood donor samples...

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Identifiers

PMID: 25955572
DOI: 10.1371/journal.pone.0125460
PMCID: PMC4425487

Genes

HFE
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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