Article
High-throughput red blood cell antigen genotyping using a nanofluidic real-time polymerase chain reaction platform.
Transfusion - 1 Jan 2010
Hopp Kathleen, Weber Kathleen, Bellissimo Daniel, Johnson Susan T, Pietz Bradley
Abstract excerpt
BACKGROUND: Serologic testing of donors to obtain antigen-negative blood for transfusion is limited by availability and quality of reagents. Where sequence variant information is available, molecular typing platforms can be used to determine the presence of a variant allele and offer a high-throughput format correlated to the blood group antigen. We have investigated a flexible high-throughput platform to screen...
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