Article
Association of the ACE I/D gene polymorphisms with JAK2V617F-positive polycythemia vera and essential thrombocythemia.
Genetic testing and molecular biomarkers - 1 Jun 2015
Gorukmez Orhan, Sag Şebnem Ozemri, Gorukmez Özlem, Ture Mehmet, Topak Ali, Sahinturk Serdar, Ozkaya Güven, Gulten Tuna, Ali Rıdvan, Yakut Tahsin
Abstract excerpt
The renin-angiotensin system contributes to cell growth, proliferation, and differentiation in the bone marrow. We investigated the role of the ACE I/D gene polymorphism in 108 polycythemia vera (PV) and essential thrombocytosis (ET) patients who were positive for the JAK2V617F mutation, with a thrombosis group (TG) of 95 patients who had a history of vascular events, but did not have a history of...
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