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Article

JAK2V617F mutation and hydroxyurea treatment as determinants of immature platelet parameters in essential thrombocythemia and polycythemia vera patients.

Blood - 1 Sept 2011

Panova-Noeva Marina, Marchetti Marina, Buoro Sabrina, Russo Laura, Leuzzi Annamaria, Finazzi Guido, Rambaldi Alessandro, Ottomano Cosimo, Ten Cate Hugo, Falanga Anna

Abstract excerpt

Immature platelets (IPFs), which are hemostatically more active than mature platelets, have been found elevated in essential thrombocythemia and polycythemia vera, 2 myeloproliferative neoplasms (MPN) characterized by an increased risk of thrombosis. It is not known whether the IPF levels are influenced by pathogenetic factors, including JAK2V617F mutational status, or by treatment regimen. To address this point,...

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Identifiers

PMID: 21750318
DOI: 10.1182/blood-2011-02-339655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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