Article
Clinical features of Japanese polycythemia vera and essential thrombocythemia patients harboring CALR, JAK2V617F, JAK2Ex12del, and MPLW515L/K mutations.
Leukemia research - 1 Jan 2016
Okabe Masahiro, Yamaguchi Hiroki, Usuki Kensuke, Kobayashi Yutaka, Kawata Eri, Kuroda Junya, Kimura Shinya, Tajika Kenji, Gomi Seiji, Arima Nobuyoshi, Mori Sinichiro, Ito Shigeki, Koizumi Masayuki, Ito Yoshikazu, Wakita Satoshi, Arai Kunihito, Kitano Tomoaki, Kosaka Fumiko, Dan Kazuo, Inokuchi Koiti
Abstract excerpt
The risk of complication of polycythemia vera (PV) and essential thrombocythemia (ET) by thrombosis in Japanese patients is clearly lower than in western populations, suggesting that genetic background such as race may influence the clinical features. This study aimed to clarify the relationship between genetic mutations and haplotypes and clinical features in Japanese patients with PV and ET. Clinical features...
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