Article
Polycythemia vera: gender-related phenotypic differences.
Internal and emergency medicine - 1 Dec 2012
Landolfi Raffaele, Di Gennaro Leonardo, Nicolazzi Maria Anna, Giarretta Igor, Marfisi RosaMaria, Marchioli Roberto
Abstract excerpt
In polycythemia vera, gender has recently been shown to influence the JAK2(V617F) allele burden, but its effect on the disease phenotype is unknown. This issue was investigated using the database of the European Collaboration on Low-dose Aspirin in Polycythemia Vera (ECLAP) Study. The ECLAP Study recruited 1,638 polycythemic subjects and followed for 2.7 ± 1.3 years. At study entry, men, compared to women, had a...
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