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Article

Novel roles of the unfolded protein response in the control of tumor development and aggressiveness.

Seminars in cancer biology - 1 Aug 2015

Dejeans Nicolas, Barroso Kim, Fernandez-Zapico Martin E, Samali Afshin, Chevet Eric

Abstract excerpt

The hallmarks of cancer currently define the molecular mechanisms responsible for conferring specific tumor phenotypes. Recently, these characteristics were also connected to the status of the secretory pathway, thereby linking the functionality of this cellular machinery to the acquisition of cancer cell features. The secretory pathway ensures the biogenesis of proteins that are membrane-bound or secreted into...

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Identifiers

PMID: 25953433
DOI: 10.1016/j.semcancer.2015.04.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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