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Article

Networks in Coronary Heart Disease Genetics As a Step towards Systems Epidemiology.

PloS one - 1 Jan 2015

Drenos Fotios, Grossi Enzo, Buscema Massimo, Humphries Steve E

Abstract excerpt

We present the use of innovative machine learning techniques in the understanding of Coronary Heart Disease (CHD) through intermediate traits, as an example of the use of this class of methods as a first step towards a systems epidemiology approach of complex diseases genetics. Using a sample of 252 middle-aged men, of which 102 had a CHD event in 10 years follow-up, we applied machine learning algorithms for the...

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PMID: 25951190
DOI: 10.1371/journal.pone.0125876
PMCID: PMC4423836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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