Article
Protein interaction-based genome-wide analysis of incident coronary heart disease.
Circulation. Cardiovascular genetics - 1 Oct 2011
Jensen Majken K, Pers Tune H, Dworzynski Piotr, Girman Cynthia J, Brunak Søren, Rimm Eric B
Abstract excerpt
BACKGROUND: Network-based approaches may leverage genome-wide association (GWA) analysis by testing for the aggregate association across several pathway members. We aimed to examine if networks of genes that represent experimentally determined protein-protein interactions (PPIs) are enriched in g...
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