Article
Effect of the rs1051730-rs16969968 variant and smoking cessation treatment: a meta-analysis.
Pharmacogenomics - 1 Jan 2015
Leung Tiffany, Bergen Andrew, Munafò Marcus Robert, De Ruyck Kim, Selby Peter, De Luca Vincenzo
Abstract excerpt
OBJECTIVE: To assess if the allelic variations of rs16969968/rs1051730 in the CHRNA5-CHRNA3-CHRNB4 gene cluster are associated with smoking cessation after nicotine replacement therapy (NRT). METHODS: We searched for NRT studies published from 2000-2013 that reported counts for allelic variation of rs16969968/rs1051730 and measured abstinence rates at the end of NRT treatment. We identified four studies which met...
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