Association of CHRNA5-A3-B4 SNP rs2036527 with smoking cessation therapy response in African-American smokers.

doi:10.1038/clpt.2014.88

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association of CHRNA5-A3-B4 SNP rs2036527 with smoking cessation therapy response in African-American smokers.

Clinical pharmacology and therapeutics - 1 Aug 2014

Zhu A Z X, Zhou Q, Cox L S, David S P, Ahluwalia J S, Benowitz N L, Tyndale R F

Abstract excerpt

Associations between CHRNA5-A3-B4 variants and smoking behaviors exist; however, the association with smoking abstinence is less understood, particularly that among African Americans. In 1,295 African Americans enrolled in two clinical trials, we investigated the association between CHRNA5-A3-B4 and smoking abstinence. The rs2056527(A) allele was associated with lower abstinence with active pharmacotherapy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Double-Blind Method

Share to Follow-Up Studies

Share to Nerve Tissue Proteins

Share to Receptors, Nicotinic

Share to Smoking

Share to Smoking Cessation

Share to Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 24733007
DOI: 10.1038/clpt.2014.88
PMCID: PMC4111775

Genes

CHRNA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of CHRNA5-A3-B4 SNP rs2036527 with smoking cessation therapy response in African-American smokers.PMID 24733007Read ↗

Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking.Semantic proximity Read ↗

Effect of the rs1051730-rs16969968 variant and smoking cessation treatment: a meta-analysis.Semantic proximity Read ↗

Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data.Semantic proximity Read ↗

Markers in the 15q24 nicotinic receptor subunit gene cluster (CHRNA5-A3-B4) predict severity of nicotine addiction and response to smoking cessation therapy.Semantic proximity Read ↗

Smoking Cessation Pharmacogenetics: Analysis of Varenicline and Bupropion in Placebo-Controlled Clinical TrialsSemantic proximity Read ↗

Organic cation transporter variation and response to smoking cessation therapies.Semantic proximity Read ↗

Cholinergic receptor nicotinic alpha 5 subunit polymorphisms are associated with smoking cessation success in women.Semantic proximity Read ↗

Nicotinic acetylcholine receptor variation and response to smoking cessation therapies.Semantic proximity Read ↗

Genetic Variant in CHRNA5 and Response to Varenicline and Combination Nicotine Replacement in a Randomized Placebo‐Controlled TrialSemantic proximity Read ↗

Helping smokers quit through pharmacogenetics.Semantic proximity Read ↗

Genome-Wide Association Study of Opioid CessationSemantic proximity Read ↗

Studies towards stratified approaches to smoking cessation with a focus on South Asians and effectiveness of vareniclineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.