Article
Endothelial progenitor cells inhibit platelet function in a P-selectin-dependent manner.
Journal of translational medicine - 7 May 2015
Abou-Saleh Haissam, Hachem Ahmed, Yacoub Daniel, Gillis Marc-Antoine, Merhi Yahye
Abstract excerpt
BACKGROUND: The role of endothelial progenitor cells (EPCs) in vascular repair is related to their recruitment at the sites of injury and their interaction with different components of the circulatory system. We have previously shown that EPCs bind and inhibit platelet function and impair thrombus formation via prostacyclin secretion, but the role of EPC binding to platelet P-selectin in this process has not been...
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