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Article

Variation in genes controlling warfarin disposition and response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCX.

Pharmacogenetics and genomics - 1 Jul 2015

Fohner Alison E, Robinson Renee, Yracheta Joseph, Dillard Denise A, Schilling Brian, Khan Burhan, Hopkins Scarlett, Boyer Bert, Black Jynene, Wiener Howard, Tiwari Hemant K, Gordon Adam, Nickerson Deborah, Tsai Jesse M, Farin Federico M, Thornton Timothy A, Rettie Allan E, Thummel Kenneth E

Abstract excerpt

OBJECTIVES: Pharmacogenetic testing is projected to improve health outcomes and reduce the cost of care by increasing therapeutic efficacy and minimizing drug toxicity. American Indian and Alaska Native (AI/AN) people historically have been excluded from pharmacogenetic research and its potential...

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Source

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Identifiers

PMID: 25946405
DOI: 10.1097/FPC.0000000000000143
PMCID: PMC4461509

Genes

VKORC1
GGCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25946405-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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