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Article

Combined analysis of CHRNA5, CHRNA3 and CYP2A6 in relation to adolescent smoking behaviour.

Journal of psychopharmacology (Oxford, England) - 1 Jul 2011

Rodriguez Santiago, Cook Derek G, Gaunt Tom R, Nightingale Claire M, Whincup Peter H, Day Ian Nm

Abstract excerpt

CYP2A6 influences smoking uptake in adolescence. Genetic variation in the CHRNA5-CHRNA3 region influences smoking behaviour in adults. However, their combined effects on smoking in adolescence have not been tested to date. We present data on 1450 adolescents from the Ten Towns Heart Health Study (TTHHS) extensively phenotyped for smoking-related traits during adolescence. Single nucleotide polymorphisms from...

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Source

Identifiers

PMID: 21765098
DOI: 10.1177/0269881111405352

Genes

CHRNA5
CHRNA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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