Article
Interindividual epigenetic variation in ABCB1 promoter and its relationship with ABCB1 expression and function in healthy Chinese subjects.
British journal of clinical pharmacology - 1 Nov 2015
Wu Lan-Xiang, Wen Chun-Jie, Li Ying, Zhang Xue, Shao Ying-Ying, Yang Zhu, Zhou Hong-Hao
Abstract excerpt
AIM: Interindividual epigenetic variation is likely to be an important mechanism contributing to the interindividual variability in the expression and function of ATP-binding cassette, sub-family B, member 1 (ABCB1). The aim of the present study was to explore the effect of interindividual epigenetic variability in the ABCB1 promoter on ABCB1 expression and function in healthy Chinese subjects. METHODS: Using...
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