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Article

Distribution of xanthine oxidase activity in a Nigerian population.

European journal of clinical pharmacology - 1 Jun 2015

Adehin Ayorinde, Bolaji Oluseye Oladotun

Abstract excerpt

BACKGROUND: Xanthine oxidase (XO) is one of the two interconvertible forms of xanthine oxidoreductase and well-studied for its role in purine catabolism and that of other purine analogues, drugs especially. Our study investigated the incidence of polymorphism in phenotypes along with the influence of gender and age on enzyme activity in a Nigerian population. METHODS: Caffeine (110 mg) was administered to each of...

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PMID: 25939710
DOI: 10.1007/s00228-015-1852-9

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