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Article

Transcriptional and proteomic analyses of two-component response regulators in multidrug-resistant Mycobacterium tuberculosis.

International journal of antimicrobial agents - 1 Jul 2015

Zhou Lei, Yang Liu, Zeng Xianfei, Danzheng Jiacuo, Zheng Qing, Liu Jiayun, Liu Feng, Xin Yijuan, Cheng Xiaodong, Su Mingquan, Ma Yueyun, Hao Xiaoke

Abstract excerpt

Two-component systems (TCSs) have been reported to exhibit a sensing and responding role under drug stress that induces drug resistance in several bacterial species. However, the relationship between TCSs and multidrug resistance in Mycobacterium tuberculosis has not been comprehensively analysed to date. In this study, 90 M. tuberculosis clinical isolates were analysed using 15-loci mycobacterial interspersed...

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Identifiers

PMID: 25937537
DOI: 10.1016/j.ijantimicag.2015.02.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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