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Cytokines in Graft-versus-Host Disease

1 May 2015

Abstract excerpt

Graft-versus-host disease (GVHD) is a complication of allogeneic bone marrow transplantation whereby transplanted naive and marrow-derived T cells damage recipient tissue through similar mechanisms to those that allow destruction of malignant cells, the therapeutic intent of bone marrow transplantation. The manifestations and severity of GVHD are highly variable and are influenced by the proportions of naive...

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PMID: 25934923
DOI: 10.4049/jimmunol.1500117

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