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Cytokine Overproduction and Immune System Dysregulation in alloHSCT and COVID-19 Patients

2 Jun 2021

Abstract excerpt

The COVID-19 pathomechanism depends on (i) the pathogenicity of the virus, (ii) ability of the immune system to respond to the cytopathic effect of the virus infection, (iii) co-morbidities. Inflammatory cytokine production constitutes a hallmark of COVID-19 that is facilitated by inability of adaptive immunity to control virus invasion. The effect of cytokine release syndrome is deleterious, but the severity of...

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PMID: 34149697
DOI: 10.3389/fimmu.2021.658896

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