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Article

Estradiol induces HOTAIR levels via GPER-mediated miR-148a inhibition in breast cancer.

Journal of translational medicine - 25 Apr 2015

Tao Sifeng, He Haifei, Chen Qiang

Abstract excerpt

HOTAIR plays an important role in the regulation of cancer cell proliferation and cancer invasion in breast cancer. The up-regulation of HOTAIR has been reported in both estrogen receptor (ER) positive and triple-negative (TN) breast cancer. It has been reported that HOTAIR is regulated by estrogen (E2) via ERs in ER-positive breast cancer. However, it is unknown how HOTAIR is regulated in TN breast cancer. In...

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Source

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Identifiers

PMID: 25928008
DOI: 10.1186/s12967-015-0489-x
PMCID: PMC4421993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Estradiol induces HOTAIR levels via GPER-mediated miR-148a inhibition in breast cancer.PMID 25928008Read ↗

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