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Article

Estradiol induces HOTAIR levels via GPER-mediated miR-148a inhibition in breast cancer.

Journal of translational medicine - 25 Apr 2015

Tao Sifeng, He Haifei, Chen Qiang

Abstract excerpt

HOTAIR plays an important role in the regulation of cancer cell proliferation and cancer invasion in breast cancer. The up-regulation of HOTAIR has been reported in both estrogen receptor (ER) positive and triple-negative (TN) breast cancer. It has been reported that HOTAIR is regulated by estrog...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25928008
DOI: 10.1186/s12967-015-0489-x
PMCID: PMC4421993

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25928008-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Estradiol induces HOTAIR levels via GPER-mediated miR-148a inhibition in breast cancer.PMID 25928008Read ↗

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Hyper-methylation of the upstream CpG island shore is a likely mechanism of GPER1 silencing in breast cancer cells.Semantic proximity Read ↗

Association of HOTAIR (rs920778 and rs1899663) and NME1 (rs16949649 and rs2302254) gene polymorphisms with breast cancer risk in India.Semantic proximity Read ↗

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