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Article

Genetic impacts on thermostability of onco-lncRNA HOTAIR during the development and progression of endometriosis.

PloS one - 1 Jan 2021

Chang Cherry Yin-Yi, Tseng Chung-Chen, Lai Ming-Tsung, Chiang An-Jen, Lo Lun-Chien, Chen Chih-Mei, Yen Man-Ju, Sun Li, Yang Li, Hwang Tritium, Tsai Fuu-Jen, Sheu Jim Jinn-Chyuan

Abstract excerpt

HOTAIR is a well-known long non-coding RNA (lncRNA) involved in various cellular signaling, whereas its functional impacts on endometriosis development are still largely unknown. To this end, six potential functional single nucleotide polymorphisms (SNPs) in HOTAIR, with minor allele frequencies more than 10% in Han population and altered net energy of RNA structures larger than 0.5 kcal/mol, were selected for...

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Share to Cell Line, Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Homeodomain Proteins

Share to Polymorphism, Single Nucleotide

Share to RNA, Long Noncoding

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Identifiers

PMID: 33667269
DOI: 10.1371/journal.pone.0248168
PMCID: PMC7935326

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